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Cleaning Validation Glossary

Product Contacting Equipment

Equipment directly interacting with products

ISPE CV Lifecycle states that product contacting equipment is equipment with surfaces that are in contact with product. Examples include interior surfaces of bioreactors, transfer tubing, and chromatography columns. PDA TR29 instructs that cleaning validation focus on product contact surfaces in equipment. Both major and minor product contact equipment items require cleaning verification or validation for multiproduct equipment.

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