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Cleaning Validation Glossary

Lower Solubility

Reduced ability of substances to dissolve

Lower solubility refers to the reduced ability of substances to dissolve. Substances with lower solubility need larger volumes of a solute in order to fully dissolve. An example of how this is used in cleaning validation is if the contaminations have a lower solubility, then more rinse solvent will be needed in order to remove the residues.

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