top of page

Cleaning Validation Glossary
Gas Chromatography (GC)
Analyzing gas mixtures
Gas chromatography (GC) is used to determine the indidual compontents of a mixed substance that is evaporated. The sample is injected and vaporized following a predetermined temperature program based on the published monograph of the analyte. A carrier gas (an inert gas such as helium, nitrogen, or hydrogen) is used to mobilize the gas produced by the substance being analyzed. The signal is meassured as a peak in relation to time. USP <621>,Chromatography, includes additional information and resources for GC and other chromatography assays.
bottom of page